Gastric Cancer

AbGn-107

Trial

Therapeutics

AbGn-107

Disease Population

The number of new cases of stomach cancer was 7.2 per 100,000 men and women per year. The number of deaths was 3.2 per 100,000 men and women per year. These rates are age-adjusted and based on 2011-2015 cases and deaths.
Approximately 0.8 percent of men and women will be diagnosed with stomach cancer at some point during their lifetime, based on 2013-2015 data.
In 2015, there were an estimated 97,915 people living with stomach cancer in the United States[1]. AbGn-107 binds to approximately 40 percent of stomach tumors.
Trial Description
This study is to define the safety profile and to determine the maximum tolerated dose (MTD) and preliminary efficacy of AbGn-107
Trial Center
Phoenix, AZ Mayo Clinic
  • Phoenix, Arizona, United States, 85054
  • Justin Weber
  • 480-342-6029
  • Weber.Justin@mayo.edu
San Francisco, CA University of California
  • San Francisco, California, United States, 94143
  • Pranay Chaurasia
  • 415-353-8449
  • Pranay.Chaurasia@ucsf.edu
Boston, MA Massachusetts General Hospital
  • Boston, Massachusetts, United States, 02114
  • Amy Gisondi
  • AGISONDI@mgh.harvard.edu
Boston, MA Beth-Israel Deaconess Medical Center
  • Boston, Massachusetts, United States, 02215
  • Justin Sun
  • 617-975-7463
  • jsun7@bidmc.harvard.edu
Boston, MA Dana-Farber Cancer Institute
  • Boston, Massachusetts, United States, 02215
  • Alexandra Bird
  • 617-632-5575
  • Alexandra_Bird@DFCI.HARVARD.EDU
Seattle, WA University of Washington, Seattle Cancer Care Alliance
  • Seattle, Washington, United States, 98109
  • Camille Biggins
  • 206-606-1646
  • cbiggins@seattlecca.org
Taichung, TW China Medical University Hospital
  • Taichung, Taiwan, 404
  • Yu-Ting Ho
  • 04-22052121 ext 5057
  • blessyou1982@gmail.com
Tainan, TW National Cheng Kung University Hospital
  • Tainan, Taiwan, 48
  • Ray-Fan Su
  • 0910-876172
  • srf106@gmail.com
Taipei, TW National Taiwan University Hospital
  • Taipei, Taiwan, 100
About Gastric Cancer
Gastric cancer (also called stomach cancer) is the fourth most common cause of cancer-related death in the world [2]. This type of cancer remains difficult to cure, primarily because it is difficult to diagnose and most patients are in advanced stages of the disease.

In most cases, stomach cancer begins from a cell that is on the inside lining of the stomach (the mucosa). This type of cancer is called adenocarcinoma. For the past several decades, rates of cancer in the main part of the stomach (stomach body) have been falling worldwide. However, incidences of gastroesophageal junction adenocarcinoma are increasing.
Citations
1. Cancer Stat Facts: Stomach Cancer. NIH. Available at
2. World Health Organization. Cancer. WHO. Available at
Details about AbGenomics Clinical Trial can be found at ClinicalTrials.gov