Pancreatic Cancer

AbGn-107

Trial

Therapeutics

AbGn-107

Disease Population

The number of new cases of pancreatic cancer was 12.6 per 100,000 men and women per year. The number of deaths was 10.9 per 100,000 men and women per year. These rates are age-adjusted and based on 2011-2015 cases and deaths.
Approximately 1.6 percent of men and women will be diagnosed with pancreatic cancer at some point during their lifetime, based on 2013-2015 data.
In 2015, there were an estimated 68,615 people living with pancreatic cancer in the United States[1]. AbGn-107 binds to approximately 50% of pancreatic tumors.
Trial Description
This study is to define the safety profile and to determine the maximum tolerated dose (MTD) and preliminary efficacy of AbGn-107
Trial Center
Phoenix, AZ Mayo Clinic
  • Phoenix, Arizona, United States, 85054
  • Justin Weber
  • 480-342-6029
  • Weber.Justin@mayo.edu
San Francisco, CA University of California
  • San Francisco, California, United States, 94143
  • Pranay Chaurasia
  • 415-353-8449
  • Pranay.Chaurasia@ucsf.edu
Boston, MA Massachusetts General Hospital
  • Boston, Massachusetts, United States, 02114
  • Amy Gisondi
  • AGISONDI@mgh.harvard.edu
Boston, MA Beth-Israel Deaconess Medical Center
  • Boston, Massachusetts, United States, 02215
  • Justin Sun
  • 617-975-7463
  • jsun7@bidmc.harvard.edu
Boston, MA Dana-Farber Cancer Institute
  • Boston, Massachusetts, United States, 02215
  • Alexandra Bird
  • 617-632-5575
  • Alexandra_Bird@DFCI.HARVARD.EDU
Seattle, WA University of Washington, Seattle Cancer Care Alliance
  • Seattle, Washington, United States, 98109
  • Camille Biggins
  • 206-606-1646
  • cbiggins@seattlecca.org
Taichung, TW China Medical University Hospital
  • Taichung, Taiwan, 404
  • Yu-Ting Ho
  • 04-22052121 ext 5057
  • blessyou1982@gmail.com
Tainan, TW National Cheng Kung University Hospital
  • Tainan, Taiwan, 48
  • Ray-Fan Su
  • 0910-876172
  • srf106@gmail.com
Taipei, TW National Taiwan University Hospital
  • Taipei, Taiwan, 100
About Pancreatic Cancer
Pancreatic cancer arises when cells in the pancreas begin to multiply out of control and form a mass. It is one of the hardest cancers to treat with a five-year relative survival rate in the single digits, at just 5-8%. It has the worst survival rate of any major cancer [2, 3].

Pancreatic cancer is hard to catch early. This is because there are no specific, cost-effective screening tests that can easily and reliably identify it in people who have no symptoms. This means it is often not found until later stages when the cancer can no longer be removed with surgery and has spread from the pancreas to other parts of the body.
Citations
1. Cancer Stat Facts: Pancreatic Cancer. NIH. Available at
2. Pancreatic Cancer Action. Facts and statistics. Available at
3. Pancreatic Cancer: Statistics. Available at
Details about AbGenomics Clinical Trial can be found atClinicalTrials.gov